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Joint Statement in Support of Scientific Discourse in Mexican GM Maize Scandal

(Click here for list of signers)

February 24, 2002 Friends,

I am sure most of you have been following the so-called Mexican maize "contamination" scandal. The research by Ignacio Chapela and David Quist of UC Berkeley published in Nature supposedly found CaMV 35S promoter sequences in Mexican maize landraces. (“Transgenic DNA introgressed into traditional maize landraces in Oaxaca, Mexico”; Nature; 29 November 2001; Vol 414, pp 541-543). This research methodology and its conclusions are however being challenged by a number of groups through formal letters to Nature (under review), and it was also addressed recently in an editorial in the journal 'Transgenic Research'.

The activists have now responded to the criticisms and challenges with a 'Joint Statement on the Mexican Maize Scandal'. This statement essentially claims that those scientific criticisms are akin to "mudslinging" and "unethical attacks" rather than simply good, vigorous scientific discourse.

Late last week, about a dozen scientists decided to respond in the form of a scientist Joint Statement, which you can read below.

If you would like to add your name to this AgBioView counter-statement, please contact us. I also encourage you to send your comments on this issue for posting on AgBioView to agbioworld@yahoo.com.

I thank all the scientists who have signed AgBioView statement.

Sincerely,

Prakash
--------

Joint Statement in Support of Scientific Discourse in Mexican GM Maize Scandal

Recently, several activist organizations and individuals signed a “Joint Statement” charging impropriety and criticizing vigorous scientific debate surrounding controversial GMO research published in Nature. The research supposedly demonstrated that Mexican landrace maize varieties had been “contaminated” with genetic material from maize varieties improved through biotechnology, presumably through cross pollination (activist statement available at foodfirst.org)

It is important to recognize that the kind of gene flow alleged in the Nature paper is both inevitable and welcome. It is inevitable because of the nature of maize, and it is welcome as demonstrated by the standard practices landrace custodians have used to improve their varieties for thousands of years -- increasing variation by planting seeds of new varieties adjacent to old ones, and then selecting the desired offspring while discarding the rest.

However, several scientists have now challenged the methodology and the results reported in the Nature paper in formal letters to Nature. The editorial board of the journal Transgenic Research found it surprising “that a manuscript with so many fundamental flaws was published in a scientific journal."

These challenges are based on the fact that the key research method employed is highly prone to false positives, and the Nature paper failed to use standard techniques to ensure accuracy and confirm results. The “joint statement” signed by the activists strongly condemns these challenges from fellow scientists as nothing more than "academic intimidation" and "a highly unethical mud-slinging campaign."

It must be stated clearly and unequivocally: scientists have a fundamental ethical obligation to rigorously examine the results and methodology of reported research. This is in fact how science corrects mistakes and ever more closely approximates truth and understanding. Far from being “mudslinging” or “intimidation,” all scientists worthy of the name understand that relentless double-checking and independent third party evaluations are the cornerstones of the scientific process.

Such relentless criticism and re-examination is perhaps most important when it leads in directions that may conflict with a point of view driven by politics or activism, rather than science.

We the undersigned scientists declare our support for appropriate and necessary scientific discourse and debate, especially in areas marked by widespread misunderstanding and misrepresentation, such as agricultural biotechnology.

Signed (as of 12:20 p.m., Wednesday, March 13, 2002),

Ingo Potrykus Professor Emeritus, Institute of Plant Sciences Swiss Federal Institute of Technology, ETH Centre Stevens M. Brumbley Senior Research Scientist Bureau of Sugar Experiment Stations
Klaus Ammann Director of the Bern Botanical Garden, Chair of the IUCN-SSC European Plants Specialist Group Switzerland Bob Goldberg Professor of Molecular, Cell, and Developmental Biology University of California
Dr. José Luis Solleiro Senior Researcher National University of Mexico Ray Wu Professor of Biochemistry and Molecular Biology Cornell University
Andrew O. Jackson Chair, Plant and Microbial Biology Dept. University of California, Berkeley Dr. Michael Mbwille, MD Food Security Network Tanzania
Michael Goodin, Ph.D. Department of Plant and Microbial Biology University of California, Berkeley Jennifer A Thomson Professor of Microbiology University of Cape Town, South Africa
Peggy G. Lemaux, Ph.D. Cooperative Extension Specialist University of California, Berkeley Dr. Chandra Prakash OSD Punjab State Council of Science & Technology, India
Sarah C. Hake Adjunct Professor University of California, Berkeley C Kameswara Rao Executive Secretary Foundation for Biotechnology Awareness and Education, India
W. Zacheus Cande Professor of Cell and Developmental Biology University of California, Berkeley Stephen K. Farrand, Ph.D. Professor of Crop Sciences and of Microbiology University of Illinois at Urbana-Champaign
Michael Freeling Professor of Genetics University of California, Berkeley Dr. Klaus M. Leisinger Executive Director Novartis Foundation for Sustainable Development
Sydney Kustu Professor of Plant and Microbial Biology University of California, Berkeley Claude Willemot Departments of Plant Science and of Food Science and Nutrition Laval University, Canada
David M. Braun Postdoctoral Researcher University of California, Berkeley Joseph M. Cleary Adjunct Professor San Diego State University
Sheila McCormick Adjunct Professor University of California, Berkeley Diana M. Horvath, Ph.D. Science Director ATP Capital LP
Nick Kaplinsky Graduate Student University of California, Berkeley Indu B. Maiti, Principal Investigator, Scientist III Molecular Plant Virology and Plant Genetic Engineering Laboratory, Biotechnology and Plant Genetic Engineering Research and Services, University of Kentucky Lexington
Susan Jenkins Research Specialist University of California, Berkeley John Kemp Molecular Geneticist New Mexico State University
Jennifer Pfluger Ph.D. Candidate University of California at Berkeley Veli Kauppinen Research professor of Biotechnology Emeritus Technical Research Center of Finland
Jim Tepperman UC Berkeley / USDA Plant Gene Expression Center Albany, CA Joseph P. Mascarenhas Department of Biological Sciences University at Albany, State University of New York
Cheryl Hackworth Graduate Student University of California, Berkeley David Mardon, B.Sc., M.F.A. Laboratory Instructor in Chemistry University College of the Cariboo, Canada
J. Peter Coppinger Graduate Student University of California, Berkeley Steven McCommas Associate Professor, Dept. of Biological Sciences Southern Illinois University, Edwardsville
Vanessa Handley Graduate Student University of California, Berkeley Muffy Koch Biosafety Consultant Innovation Biotechnology, South Africa
Zhangliang Chen Professor of Biotechnology and Vice President Beijing University Dr. Peter Langelüddeke Retired, Hoechst AG
Swapan K. Datta Plant Biotechnologist International Rice Research Institute (IRRI), Philippines Susan Harlander, Ph.D. President, BIOrational Consultants, Inc. New Brighton, Minnesota
Dr Philippe Joudrier Director of research Institut National de la Recherche Agronomique, France Piero Morandini Section for Plant Physiology and Biochemistry University of Milan, Italy
Neal Stewart Associate Professor Univerity of North Carolina, Greensboro Erin Irish Associate Professor University of Iowa
Boris Levenko Head of Department Institute of Plant Physiology & Genetics, Ukrainian Academy Sciences Andrew D. Powell, Ph.D. President ARB Consultants
Corrado Fogher Professor of Genetics and Plant Breeding Università Cattolica S. Cuore, Italy Sarah Wyatt Assistant Professor, Plant Biology Ohio University, Athens, OH
Tony Shelton Professor,Department of Entomology Cornell University Rob Martienssen, PhD Professor Cold Spring Harbor Laboratory
Matt Metz Postdoctoral Fellow University of Washington, Seattle Gregory Edmeades Research Fellow Waimea Research Station, Pioneer Hi-Bred International
Martina Newell McGloughlin Director and Adjunct Professor University of California, Davis Hector Quemada Adjunct Professor of Biological Sciences, Western Michigan University and President, Crop Technology Consulting, Inc.
Bruce Chassy Executive Associate Director of the Biotechnology Center University of Illinois at Urbana-Champaign Dean W. Gabriel Professor of Plant Molecular & Cell Biology University of Florida, Gainesville
C. R. Bhatia Former Secretary, Department of Biotechnology New Bombay, India Khusi R. Tiwari, Ph.D. Research Scientist Pioneer Hi-Bred International, Inc.
Rick Roush Cooperative Research Centre for Australian Weed Management University of Adelaide, Australia Herb S. Aldwinckle Professor of Plant Pathology Cornell University
C.S. Prakash Professor of Plant Molecular Genetics Tuskegee University, Alabama, USA Peter Klosterman Postdoctoral researcher The Buck Institute, Novato, CA.
Douglas Powell Assistant professor, Department of Plant Agriculture University of Guelph, Canada Jeff M. Hall, PhD Vice President of Cell Biology Genoptix, Inc.
Henry Miller The Hoover Institution Stanford University David Cove Professor of Genetics, University of Leeds Centre for Plant Sciences
Tom DeGregori Professor of Economics University of Houston Allan S. Felsot
Professor & Extension Specialist
Washington State University

Alex Avery
Director of Research and Education
Center for Global Food Issues

Carlos F. Quiros
Department of Vegetable Crops
University of California

Mark P. Running
Assistant Member, Principal Investigator
Donald Danforth Plant Sciences Center

Detlef Bartsch, PhD
Aachen University of Technology RWTH
Germany

Yiji Xia
Principal Investigator
Donald Danforth Plant Science Center

Dr. Vivek Damle
Chairman, SAVIDA Agri-Com Pvt. Ltd
Mumbai, India

Jean B Bergé
Chef de Département Adjoint Département
Institut National de la Recherche Agronomique, France

Roger Frutos
CIRAD
Montpellier, France

Mark Tepfer
Research scientist
Institut National de la Recherche Agronomique, France

Randy A. Hautea
International Service for the Acquisition of
Agri-biotech Applications
Los Baños, Philippines

David E Tribe
Department of Microbiology and immunology
University of Melbourne

James D. Wilson, Ph.D.
Resources for the Future
Washington, DC

Maurice M Moloney
Professor and NSERC Chair of Plant Biotechnology
University of Calgary, Canada

Paul Robson
Project Leader
Institute of Grassland and Environmental Research, UK

Jose A. Feijo
Professor of Plant Biology, Univ. Lisboa, Portugal
Senior Researcher, Gulbenkian Institute for Science, Portugal

Pia Rufener Al Mazyad
Botanical Garden
University of Berne, Switzerland

Pere Arus
Departament de Genetica Vegetal
IRTA-Cabrils, Spain

Jumin Tu
Senior Research Scientist, Department of Biology
The Chinese University of Hong Kong

Paul Geiger
Associate Professor Emeritus
University of Southern California School of Medicine

Robert Wager
Biology Department
Malaspina University College, Canada

Drew L. Kershen
Earl Sneed Centennial Professor of Law
University of Oklahoma

Shantu Shantaram
Head, Stakeholder and Technology Communications Syngenta Seeds, Inc.
Hans Holtan
Graduate Student
University of California at Berkeley

Dr. Peng Zhang
Institute for Plant Sciences
ETH-Zentrum, Switzerland
William Hutchison
Professor, Entomology
University of Minnesota

Richard Braun
Prof. em. of Microbiology
University of Bern, Switzerland

Dr. Roberto Defez
IGB, National Research Council
Naples, Italy

Victor M. Nunez
Head of National Plant Genetic Rsources and Plant Biotechnology Program
CORPOICA Colombia

Professor T Michael A Wilson FRSE
Chief Executive
Horticulture Research International