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July 6, 2000


Antibiotic marker genes


AgBioView - http://www.agbioworld.org, http://agbioview.listbot.com

Subj:Antibiotic marker genes
Date:Thu, 6 Jul 2000 3:38:31 PM Eastern Daylight Time
From:Greg Conko
To:"'Klaus Ammann'" , "'AgBioView'"

It's worth noting that the aminoglycoside 3'-phosphotransferase II
selectable marker for kanamycin resistance incorporated into the Calgene
FlavrSavr tomato, was evaluated by the United States Food and Drug
Administration as a food additive (FDA Docket Nos. 90A-0416 and 91A-0330).
This is not generally known, however.
Indeed, many advocates of stricter GMO testing in the United States,
including several members of the US Congress, argue that GM foods should
be regulated under the procedures for evaluating food additives, which are
somewhat more restrictive than those under the FDA's Statement of Policy
on Foods Derived from New Plant Varieties (57 Fed. Reg. 22984, May 29,

If these people do indeed believe that evaluation of GM foods as food
additives is necessary and sufficient for ensuring their safety, I submit
that they have no reasonable grounds for questioning the safety of this
kanamycin-resistant marker gene.

-Greg Conko

-----Original Message-----
From: Klaus Ammann [mailto:kammann@sgi.unibe.ch]
Sent: Tuesday, July 04, 2000 1:22 PM
To: klaus.ammann@sgi.unibe.ch
Subject: Debate 2000'0704 a: Antibiotic marker genes: A thorough view

Conclusion: The Amp gene in genetically modified maize is not of
significant risk because 1) An intact ori-Amp sequence is
extremely unlikely to survive the hostile conditions

Dear friends,

Everything you always wanted to know about antibiotic marker genes, here
is the text with over 100 scientific references.

Happy (and long !!) reading.

Always if authors are getting into a really scientific debate about the
antibiotic marker genes, leaving out all political elements, they come to
the conclusion that risks are astronomically minimal.


Thanks to Prakash and his agbioworld bringing up such important texts

AgBioView - http://www.agbioworld.org, http://agbioview.listbot.com



those who want to get a word file should email again.

Prof. Dr. Klaus Ammann
Director Botanical Garden,
University of Bern
Altenbergrain 21
CH - 3013 Bern, Switzerland
Tel. +41 31 631 49 37
Fax +41 31 631 49 93